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An Overview of the Epidemiology, Pathogenesis, Diagnosis, and Treatment of Human Parvovirus B19

  • Kumaran Vadivel
  • Balaji Nandagopal
  • Mageshbabu Ramamurthy
  • Nithiyanandan Saravanan
  • Prashanth Rajendiran

Asian Journal of Research in Infectious Diseases, Page 32-43
DOI: 10.9734/ajrid/2022/v11i4226
Published: 1 December 2022

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Abstract


Human Parvovirus B19 (HPV-B19) infections are reported from different parts of the globe. The infection occurs in all age groups; however, most infections occur in childhood. There is evidence of exposure to the virus in about 80% of adults when screened for specific IgG. HPV-B19 is incriminated in several conditions like erythema infectious, aplastic crisis, hydrops fetalis and arthropathy. HPV-B19 is a cause of the Fifth disease (erythema infectious); it could also cause a febrile illness with or without rash in adults. Many adults especially women develop arthropathy and the condition could be chronic following a febrile illness. Patients (adults) with End Stage Renal Disease (ESRD) are prone to develop aplastic crisis or chronic anemia [1].  This review article aims to comprehensively describe the etiology, epidemiology, clinical features, diagnostic methods, and treatment in the management of HPV-B19.


Keywords:
  • Arthropathy
  • End-stage renal disease
  • febrile illness
  • IgM
  • HPV-B19
  • Full Article - PDF
  • Review History

How to Cite

Vadivel, K., Nandagopal, B., Ramamurthy, M., Saravanan, N., & Rajendiran, P. (2022). An Overview of the Epidemiology, Pathogenesis, Diagnosis, and Treatment of Human Parvovirus B19. Asian Journal of Research in Infectious Diseases, 11(4), 32-43. https://doi.org/10.9734/ajrid/2022/v11i4226
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