Renal and Hemorrhagic Complications Following Bee Sting Envenomation: A Case Report from the Hospital of Zinder

Doutchi Mahamadou *

Faculty of Health Sciences, André Salifou University, Zinder, Niger and National Hospital of Zinder, Niger.

Lamine Mahaman Moustapha

National Hospital of Zinder, Niger and Faculty of Science and Technology, André Salifou University, Zinder, Niger.

Bagnou Hamsatou

National Hospital of Zinder, Niger.

Souleymane Adoum Fils

Faculty of Health Sciences, André Salifou University, Zinder, Niger.

Adamou Bara Abdoul-Aziz

Faculty of Health Sciences, André Salifou University, Zinder, Niger.

Garba Abdoul Aziz

Faculty of Health Sciences, André Salifou University, Zinder, Niger and National Hospital of Zinder, Niger.

Adehossi Eric

Faculty of Health Sciences, Abdou Moumouni University, Niamey, Niger.

*Author to whom correspondence should be addressed.


Abstract

Renal and hemorrhagic complications following envenomation by bee stings are rare, posing significant problems for early diagnosis and treatment in the clinical setting. Bee venom is generally well tolerated. A 44-year-old patient was admitted to the infectious and tropical diseases department of the Zinder National Hospital with cervicofacial edema following bee stings. Initially, the patient lost consciousness. Respiratory symptoms included dyspnea and 91% desaturation on room air. The patient was put on oxygen to alleviate hypoxia, doxycycline to prevent secondary bacterial infections, and prednisone to reduce inflammation. The clinical picture was complicated by a worsening of the patient's condition due to a deterioration in renal function, and the subsequent appearance of hematemesis.  A renal biopsy revealed acute tubulointerstitial nephropathy, due to direct venom toxicity on the tubules. He was discharged after 35 days. We report a rare case of bee sting complicated by hemorrhagic syndrome and renal involvement.

Keywords: bees, envenomation, kidney complications, hemorrhages, Zinder, Niger Republic


How to Cite

Mahamadou, Doutchi, Lamine Mahaman Moustapha, Bagnou Hamsatou, Souleymane Adoum Fils, Adamou Bara Abdoul-Aziz, Garba Abdoul Aziz, and Adehossi Eric. 2024. “Renal and Hemorrhagic Complications Following Bee Sting Envenomation: A Case Report from the Hospital of Zinder”. Asian Journal of Research in Infectious Diseases 15 (7):18-23. https://doi.org/10.9734/ajrid/2024/v15i7358.

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References

Chowdhury FR, Bari MS, Shafi AM, Ruhan AM, Hossain ME, Chowdhury S, et al. Acute Kidney Injury Following Rhabdomyolysis due to Multiple Wasp Stings (Vespa affinis). Asia Pac J Med Toxicol. 1 mars. 2014;3(1):41‑3.

Deshpande PR, Farooq AK, Bairy M, Prabhu RA. Acute Renal Failure and/or Rhabdomyolysis due to Multiple Bee Stings: A Retrospective Study. North Am J Med Sci. mars 2013;5(3):235‑9.

Almeida RAM de B, Olivo TET, Mendes RP, Barraviera SRCS, Souza L do R, Martins JG, et al. Africanized honeybee stings: how to treat them. Rev Soc Bras Med Trop. déc 2011;44:755‑61.

Berdai MA, Labib S, El Balbal M, Harandou M. Piqures massives par un essaim d’abeilles chez un enfant. Pan Afr Med J. 2011;10.

Sullerot I, Birnbaum J, Girodet E. Le syndrome d’envenimation massive à propos d’un cas clinique de piqûres multiples discuté par le groupe «insectes» de la SFA. Rev Fr Allergol. 2013;53 (1):50‑2.

Schumacher MJ, Tveten MS, Egen NB. Rate and quantity of delivery of venom from honeybee stings. J Allergy Clin Immunol. mai 1994;93(5):831‑5.

Betten DP, Richardson WH, Tong TC, Clark RF. Massive honey bee envenomation-induced rhabdomyolysis in an adolescent. Pediatrics. janv 2006;117(1):231‑5.

LoVecchio F, Cannon RD, Algier J, Ruha AM, Curry SC, Wallace KL, et al. Bee swarmings in children. Am J Emerg Med. 1 Oct 2007;25(8):931‑3.

Przybilla B, Ruëff F. Insect Stings. Dtsch Ärztebl Int. mars 2012;109(13):238‑48.

Prado M, Quirós D, Lomonte B. Mortality due to Hymenoptera stings in Costa Rica, 1985-2006. Rev Panam Salud Pública. mai 2009;25(5):389‑93.

Golden DBK, Moffitt J, Nicklas RA, Freeman T, Graft DF, Reisman RE, et al. Stinging insect hypersensitivity: A practice parameter update 2011. J Allergy Clin Immunol. 1 avr 2011;127(4):852-854.e23.

Mass envenomations by honey bees and wasps - PubMed [Internet]. Disponible sur.

Available :https://pubmed.ncbi.nlm.nih.gov/10344177/

[Accessed on: 6 janv 2024].

Abayi DM, Mengome EM. Lésions oculaires par piqûre d’abeille: à propos d’un cas. J Fr Ophtalmol. 2021;44 (4):e191‑3.

Azad C, Parmar VR, Jat KR. Unusual fatal multiple-organ dysfunction and pancreatitis induced by a single wasp sting. J Venom Anim Toxins Trop Dis. 2011;17: 108‑10.

Guimarães JV, Costa RS, Machado BH, Reis MA dos. Cardiovascular profile after intravenous injection of Africanized bee venom in awake rats. Rev Inst Med Trop São Paulo. févr 2004;46:55‑8.

BOURGAIN C, PAUTI MD, FILLASTRE JP, GODIN M, FRANCOIS A, LEROY JP, et al. Envenimation massive après piqûres d’abeilles africaines. Envenimation Massive Après Piqûres Abeilles Afr. 1998;27(22):1099‑101.

Shah D, Tsang TK. Bee sting dysphagia. Ann Intern Med. 1 août 1998;129(3):253.

[Ocular lesions after bee sting of the cornea. A case report] Disponible sur. Available:https://pubmed.ncbi.nlm.nih.gov/19769859/

[Accessed on: 6 janv 2024].

Survival after massive (>2000) Africanized honeybee stings. Disponible sur. Available:https://pubmed.ncbi.nlm.nih.gov/9570180/

[Accessed on: 6 janv 2024].

França FO, Benvenuti LA, Fan HW, Dos Santos DR, Hain SH, Picchi-Martins FR, et al. Severe and fatal mass attacks by « killer » bees (Africanized honey bees--Apis mellifera scutellata) in Brazil: clinicopathological studies with measurement of serum venom concentrations. Q J Med. mai 1994;87(5): 269‑82.