Open Access Review Article

Post-viral Fatigue: Implications for Long Covid

A. P. Smith

Asian Journal of Research in Infectious Diseases, Page 17-23
DOI: 10.9734/ajrid/2021/v6i130182

There has been extensive research on post-viral fatigue, and the present mini-review and commentary provides an overview of the effects associated with different infecting agents. Fatigue is not only a subjective state, rather it has an impact on our ability to carry out everyday functions, and its effect can be demonstrated using performance tasks. It is not surprising, therefore, that persistent effects of COVID-19 are observed, and the key features of Long Covid are reviewed here, Suggestions for further research which will provide a better understanding of Long Covid and provide a basis for prevention and management are also discussed.

Open Access Original Research Article

Clinical Symptoms and Haematological Characteristics among Male and Female COVID-19 Patients in Rivers State: A Single-center Case Reviews

Alali Dan- Jumbo, Tondor Cleopatra Uzosike, Mary Obidiya Okuku

Asian Journal of Research in Infectious Diseases, Page 8-16
DOI: 10.9734/ajrid/2021/v6i130180

Objectives: The study seeks to assess the sex differences in reported clinical symptoms and haematological parameters of hospitalized COVID-19 cases.

Study Design: A retrospective descriptive cross-sectional study.

Place and Duration of Study: Covid-19 Treatment Centre, Rivers State, between May 2020 and July 2020.

Methodology: Descriptive data collection for patients diagnosed of COVID-19 was employed within the months of May to July 2020. A comparison of demographic profile, presenting symptoms, comorbidities and laboratory findings between males and females was analyzed using SPSS version 25. Ethical approval was obtained prior to commencing data collection.

Results: In this study, data of 56 patients were analyzed of which 31 (55.4%) were males and 25 (44.6%) were females. The mean age for all patients was 36 years and males had a higher mean age (40 ± 12.6) compared to females (31 ± 8.8). Twelve patients (21.4%) reported pre-existing co-morbidities and Hypertension 11 (19.6%) was the prevalent co-morbidity followed by peptic ulcer 2 (3.6%) and Diabetes 2 (3.6%) and these were more common among males. Triglyceride level was significantly higher among females (p= 0.028) and low-density lipoprotein (LDL) level was significantly lower among females (p= 0.044) while systolic blood pressure level was significantly higher among males (p= 0.011).

Conclusion: Though similar symptoms and haematological findings occur in males and females, specific disparities in some parameters were observed. We recommend healthcare personnel to consider these differences when caring for patients hospitalized for COVID-19.

Open Access Original Research Article

Efficacy of Commonly Used Mosquito Coils Containing Pyrethrin against Lymphatic Filariasis Vector Culex quinquefasciatus (Say) in Gombe

Abdulmalik Bala Shuiabu, Muhammed Ishaku, Kennedy Poloma Yoriyo, Ezra Abba, Ahmadu Bukar, Musa Umar Umar

Asian Journal of Research in Infectious Diseases, Page 32-39
DOI: 10.9734/ajrid/2021/v6i130184

Aims: Mosquito coil is a common insect repellant used in many homes to repel and kill mosquitoes that transmit diseases and another insect pest. The present study was conducted to explore the potency of the commonly used brand of mosquito coil containing pyrethroids against Culex quinquefasciatus in Gombe and its communities.

Place and Duration of Study: Department of Biological sciences insectary laboratory of Gombe State University, Gombe, Nigeria between August and December 2017.

Methodology: Four (4) different brands tagged; C1, C2, C3 and C4 containing 0.08% Merperflutrin, 0.2% Pyrethroids, 0.05% Transflutrine + 0.1% Esbiothrin and 0.25% d-Trans-allethrin respectively were investigated. Ten (10) reared adult mosquitoes were transferred separately into various containers using an aspirator. Data on knockdown time and Adult mortality were recorded.  All the data collected were analyzed using SPSS version 24.0. Analysis of Variance (ANOVA) was used to determine the significant difference between the treatments at P=.05.  

Results: Merperflutrin 0.08%, Transflutrine 0.05% + Esbiothrin 0.1% and 0.25% d-Transalletrin recorded highest mortality of 100% each and 0.2% Pyrethroids recorded 96% mortality at 24hours of exposure to the treatment respectively. The mortality is time- dependent and all the treatments show significant mortality at P=.05. Transflutrine 0.05% + Esbiothrin 0.1% recorded the lowest KT50 value of 2.41 min.

Conclusion: Merperflutrin 0.08%, and Transflutrine 0.05% + Esbiothrin 0.1% have the highest efficacy; faster knockdown rate and could be used as a repellent in minimizing the population of the indoor resting density of mosquitoes’ species in our homes.

Open Access Minireview Article

What Makes the Elderly Prone to Parasitic Infection?

Forman Erwin Siagian, Esy Maryanti

Asian Journal of Research in Infectious Diseases, Page 24-31
DOI: 10.9734/ajrid/2021/v6i130183

The number of the elderly is increasing globally, and as a consequence the number of geriatric health problems also increased, including parasitic infection. The skin and the GI tract were among the most common locations of parasitic infections of the elderly. Underlying biological and social problems can prevent their independence in maintaning basic personal hygiene which made them depend on other’s help, permanently. These seniors sometimes become the permanent residence of nursing homes. their dependence made them attached very close to the staff or other helper, even maintaining the basic function of life like eating. If this helper actually a parasitic agent carrier, parasitic infection transmission will be made easy by this symbiotic relationship. Besides behavior, some biological factors, e.g immunosenescence and or organ dysfunction, may contribute to infection.

Open Access Case Study

Febrile Polyarthritis: Should We Think About Disseminated Gonococcal Infection

Mariem Ghribi, Sameh Marzouk, Abir Derbel, Mouna Snoussi, Zouhir Bahloul

Asian Journal of Research in Infectious Diseases, Page 1-7
DOI: 10.9734/ajrid/2021/v6i130179

Gonococcal disease is a sexually transmitted infection. The responsible agent is Neisseria gonorrhoeae. Disseminated gonococcal infection results from blood dissemination of N. gonorrhoeae from its mucosal first site of infection. In our cases, two patients had systematic lupus erythematous, in which one patient developed a dermetitis-arthritis syndrome and the other patient developed a febrile polyarthritis. The third patient was a healthy female who developed a dermetitis-arthritis syndrome. The treatment consisted of intravenous antibiotic and immobilization. The evolution was favorable in all of our cases.